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COX-2/PGE2 pathway is amplified in murine and human diabetic monocytes/macrophages. Unsuitable PGE2 action might keep the inflammatory phenotype of wound macrophages, which isn't conducive into the fix of diabetic wounds 37. The duality of PGE2 as well as complexity of the human body require us to check out a lot more to uncover the better therapeu
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